Red Sox Yankees Opening Day 2025. We'll get our first look at boston's loaded lineup friday afternoon when the red sox play their opening day game against the rival new york yankees at yankee. Traditional opening day, featuring all 30 major league clubs, will take place the week after on thursday, march 28.

By ronald blum • published april 8, 2022 • updated on april 8, 2022 at 6:33 pm. If you missed any of the previous projections,.